CyanoFactory is a collaborate research project for design, construction and demonstration of solar biofuel production using novel (photo)synthetic cell factories.
About CyanoFactory KB
CyanoFactory KB is a knowledge base that is embracing all data produced by and relevant to the CyanoFactory project partners.
It is designed specifically to enable comprehensive, dynamic simulations of entire cells and organisms. CyanoFactory KB is currently centered around Synechocystis PCC 6803, an extremely small gram-negative bacterium that is capable of photosynthesis and provides comprehensive, quantitative descriptions of individual mutant strains including:
- Cellular chemical composition,
- Growth medium composition,
- Gene locations, lengths, and directions,
- Transcription unit organization and transcriptional regulation,
- Macromolecule composition,
- Reaction stoichiometry, kinetics, and catalysis,
- Extensive links and cross-links to all references used to construct each database, and
- Experimental conditions.
The best ways to get started are to browse or search this database using the menu or the search box at the top of this page.
CyanoFactory KB has been developed and further extended on the basis of WholeCellKB (Karr JR, Sanghvi JC, Macklin DN, Arora A, Covert MW.)
WholeCellKB: Model Organism Databases for Comprehensive Whole-Cell Models. Nucleic Acids Research 41, D787-D792 (2013). Nucleic Acids Research | PubMed, Karr JR, Sanghvi JC, Macklin DN, Gutschow MV, Jacobs JM, Bolival B, Assad-Garcia N, Glass JI, Covert MW. A Whole-Cell Computational Model Predicts Phenotype from Genotype. Cell 150, 389-401 (2012). Cell | PubMed
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